Los Angeles Rams vs. San Francisco 49ers NFL Week 10 Odds, Plays and Insights

Check out odds, plays and more for the Los Angeles Rams vs. San Francisco 49ers NFL Week 10 matchup on November 15, 2021.

The Los Angeles Rams (7-2) and San Francisco 49ers (3-5) will battle in a Week 10 NFL clash of NFC West foes.

For more great betting and fantasy insight, join the SI Winners Club Newsletter.

Odds for Rams vs. 49ers

View the original article to see embedded media.

Los Angeles has combined with its opponents to score more than 49 points in five of nine games this season.
San Francisco and its opponents have combined to score more than 49 points in four of eight games this season.
The two teams combine to average 52.1 points per game, 3.1 more than the total in this contest.
This contest’s over/under is 1.9 points more than the 47.1 these two squads combine to surrender per game this season.
The Rams and their opponents have scored an average of 50.7 points per game in 2020, 1.7 more than Monday’s total.
The 49 total in this game is 2.2 points above the 46.8 average total in 49ers games this season.

Los Angeles has played nine games, with four wins against the spread.
This season, the Rams have just two ATS wins in seven games as a favorite of 3.5 points or more.
Los Angeles’ games this year have gone over the point total five times in nine opportunities (55.6%).
The Rams rack up 29.0 points per game, 3.7 more than the 49ers surrender per outing (25.3).
When Los Angeles scores more than 25.3 points, it is 4-3 against the spread and 7-0 overall.
The Rams collect 61.2 more yards per game (399.3) than the 49ers allow per outing (338.1).
In games that Los Angeles piles up more than 338.1 yards, the team is 4-5 against the spread and 7-2 overall.
This year, the Rams have turned the ball over nine times, four more than the 49ers’ takeaways (5).
Click over to SISportsbook and find the latest spread, moneyline and total for Los Angeles’ matchup with the 49ers.

San Francisco has two wins against the spread in eight games this season.
The 49ers have been underdogs by 3.5 points or more one time this year and have not covered the spread once.
San Francisco’s games this season have gone over the point total five times in eight opportunities (62.5%).
This season the 49ers put up just 1.3 more points per game (23.1) than the Rams allow (21.8).
When San Francisco records more than 21.8 points, it is 1-2 against the spread and 2-1 overall.
The 49ers collect only 17.4 more yards per game (365.6) than the Rams give up per contest (348.2).
San Francisco is 1-2 against the spread and 2-1 overall when the team totals more than 348.2 yards.
The 49ers have 14 giveaways this season, while the Rams have 14 takeaways.

San Francisco is winless against the spread, and 0-4 overall, at home this season.
At home, as 3.5-point underdogs or greater, the 49ers are winless ATS (0-3).
In four games at home this season, San Francisco has gone over the total three times.
This season, 49ers home games average 47.8 points, 1.2 fewer than this outing’s over/under (49).
Los Angeles has two wins against the spread, and is 4-0 overall, away from home.
The Rams have one win ATS (1-2) away from home as 3.5-point favorites or more.
Los Angeles has gone over the total twice in four away games this season.
Rams away games this season average 49.4 total points, 0.4 more than this matchup’s over/under (49).